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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
13
|
| pubmed:dateCreated |
1999-1-29
|
| pubmed:abstractText |
A unique heterodimeric naphthylisoquinoline alkaloid, korundamine A (2), comprised of two different monomeric biaryl halves, has been isolated from the Cameroonian tropical liana Ancistrocladus korupensis. Korundamine A is the first "hybrid" dimer found in the Ancistrocladaceae; in vitro, it demonstrated anticytopathic activity against HIV-1 and antimalarial activity against Plasmodium falciparum.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
7
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1729-34
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9873424-Animals,
pubmed-meshheading:9873424-Anti-HIV Agents,
pubmed-meshheading:9873424-Antimalarials,
pubmed-meshheading:9873424-Cytopathogenic Effect, Viral,
pubmed-meshheading:9873424-Dimerization,
pubmed-meshheading:9873424-HIV-1,
pubmed-meshheading:9873424-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9873424-Naphthalenes,
pubmed-meshheading:9873424-Plants,
pubmed-meshheading:9873424-Plasmodium falciparum,
pubmed-meshheading:9873424-Quinolines,
pubmed-meshheading:9873424-Spectrometry, Mass, Fast Atom Bombardment
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Korundamine A, a novel HIV-inhibitory and antimalarial "hybrid" naphthylisoquinoline alkaloid heterodimer from Ancistrocladus korupensis.
|
| pubmed:affiliation |
Laboratory of Drug Discovery Research and Development, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|