rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
12
|
pubmed:dateCreated |
1999-2-1
|
pubmed:abstractText |
Novel 1-(1-benzoylindoline-5-sulfonyl)-4-phenyl-4,5-dihydroimidazolon es 3 synthesized show highly potent and broad cytotoxicities. Among them compound 3b (DW2143) exhibits much more potent cytotoxicities than doxorubicin and highly effective antitumor activities against murine (3LL, Colon 26) and human xenograft (NCI-H23, SW620) tumor models.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0960-894X
|
pubmed:author |
pubmed-author:ChungY HYH,
pubmed-author:CookN SNS,
pubmed-author:HwangH SHS,
pubmed-author:JungS HSH,
pubmed-author:LalK BKB,
pubmed-author:LeaII,
pubmed-author:LeeC WCW,
pubmed-author:LeeD KDK,
pubmed-author:LeeH SHS,
pubmed-author:LeeJ AJA,
pubmed-author:LowF NFN,
pubmed-author:MoonE YEY,
pubmed-author:SeongS KSK,
pubmed-author:SongJ SJS,
pubmed-author:YoonS JSJ
|
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1547-50
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9873387-Animals,
pubmed-meshheading:9873387-Antineoplastic Agents,
pubmed-meshheading:9873387-Drug Screening Assays, Antitumor,
pubmed-meshheading:9873387-Humans,
pubmed-meshheading:9873387-Imidazoles,
pubmed-meshheading:9873387-Mice,
pubmed-meshheading:9873387-Sulfones,
pubmed-meshheading:9873387-Transplantation, Heterologous,
pubmed-meshheading:9873387-Tumor Cells, Cultured
|
pubmed:year |
1998
|
pubmed:articleTitle |
Synthesis and antitumor activity of 4-phenyl-1-arylsulfonyl imidazolidinones.
|
pubmed:affiliation |
College of Pharmacy, Chungnam National University, Taejon, Korea.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|