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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1999-3-10
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pubmed:abstractText |
Lymphoepithelial carcinoma is a relatively common malignancy in the nasopharynx, but it rarely occurs at other sites. Described herein is the first case of a renal pelvic neoplasm that closely resembled lymphoepithelial carcinoma, with analyses of histology, immunophenotype, in situ hybridization for the Epstein-Barr viral genome, and flow cytometric DNA ploidy. The tumor was detected in an 70-year-old Japanese man who presented with hematuria Histologic examination showed an undifferentiated round or spindle cell carcinoma (cytokeratin 7+, cytokeratin 20+, epithelial membrane antigen+, vimentin-) with abundant lymphocytes (predominantly UCHL-1+ T cells), plasma cells, and macrophages in and around the tumor cell nests. The tumor was limited to the pelvis, with a minute focus of carcinoma in situ. No Epstein-Barr viral genomic sequences were detected by in situ hybridization. The tumor had an aneuploid DNA content. The patient remains well without disease 6 years after surgery and radiotherapy. Recognition of this type of renal pelvis carcinoma is important to avoid misdiagnosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0893-3952
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1252-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9872659-Aged,
pubmed-meshheading:9872659-Aneuploidy,
pubmed-meshheading:9872659-Carcinoma, Squamous Cell,
pubmed-meshheading:9872659-DNA, Neoplasm,
pubmed-meshheading:9872659-DNA, Viral,
pubmed-meshheading:9872659-Flow Cytometry,
pubmed-meshheading:9872659-Genome, Viral,
pubmed-meshheading:9872659-Herpesviridae Infections,
pubmed-meshheading:9872659-Herpesvirus 4, Human,
pubmed-meshheading:9872659-Humans,
pubmed-meshheading:9872659-Immunoenzyme Techniques,
pubmed-meshheading:9872659-In Situ Hybridization,
pubmed-meshheading:9872659-Kidney Neoplasms,
pubmed-meshheading:9872659-Kidney Pelvis,
pubmed-meshheading:9872659-Male,
pubmed-meshheading:9872659-Tumor Markers, Biological,
pubmed-meshheading:9872659-Tumor Virus Infections
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pubmed:year |
1998
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pubmed:articleTitle |
Lymphoepithelioma-like carcinoma of the renal pelvis: a case report with immunohistochemical analysis and in situ hybridization for the Epstein-Barr viral genome.
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pubmed:affiliation |
Department of Pathology, Jikei University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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