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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
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pubmed:dateCreated |
1999-3-11
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|
pubmed:abstractText |
A new series of 4-substituted pipecolic acid derivatives was prepared and incorporated into dipeptoids. The resulting products behave as moderately potent CCK-B antagonists but their constrained structure and its comparison with structurally related compounds yield valuable information about the conformational requirements for optimal recognition of the CCK-B receptor by antagonists.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0960-894X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:day |
2
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1419-24
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:9871777-Animals,
pubmed-meshheading:9871777-CHO Cells,
pubmed-meshheading:9871777-Cerebral Cortex,
pubmed-meshheading:9871777-Cholecystokinin,
pubmed-meshheading:9871777-Cricetinae,
pubmed-meshheading:9871777-Guinea Pigs,
pubmed-meshheading:9871777-Models, Molecular,
pubmed-meshheading:9871777-Molecular Conformation,
pubmed-meshheading:9871777-Pancreas,
pubmed-meshheading:9871777-Pipecolic Acids,
pubmed-meshheading:9871777-Protein Conformation,
pubmed-meshheading:9871777-Rats,
pubmed-meshheading:9871777-Receptor, Cholecystokinin B,
pubmed-meshheading:9871777-Receptors, Cholecystokinin,
pubmed-meshheading:9871777-Structure-Activity Relationship
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|
pubmed:year |
1998
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|
pubmed:articleTitle |
Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid.
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|
pubmed:affiliation |
Département de Pharmacochimie Moléculaire et Structurale, INSERM U266, CNRS URA D1500, UFR des Sciences Pharmaceutiques et Biologiques, Paris, France.
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pubmed:publicationType |
Journal Article,
In Vitro
|
