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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1999-3-11
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pubmed:abstractText |
New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1375-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9871769-Animals,
pubmed-meshheading:9871769-Guinea Pigs,
pubmed-meshheading:9871769-Humans,
pubmed-meshheading:9871769-Muscle, Smooth, Vascular,
pubmed-meshheading:9871769-Muscle Contraction,
pubmed-meshheading:9871769-Platelet Aggregation Inhibitors,
pubmed-meshheading:9871769-Pressure,
pubmed-meshheading:9871769-Rabbits,
pubmed-meshheading:9871769-Receptors, Thromboxane,
pubmed-meshheading:9871769-Stereoisomerism,
pubmed-meshheading:9871769-Structure-Activity Relationship,
pubmed-meshheading:9871769-Sulfonamides,
pubmed-meshheading:9871769-Tetrahydronaphthalenes,
pubmed-meshheading:9871769-Trachea
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pubmed:year |
1998
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pubmed:articleTitle |
Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists.
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pubmed:affiliation |
Institut de Recherches Servier, Centre de Recherches de Croissy, Croissy-sur-Seine, France.
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pubmed:publicationType |
Journal Article,
In Vitro
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