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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1999-3-11
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pubmed:abstractText |
High affinity, selective hNK2 or hNK3 ligands can be prepared from the common template 1 in a few simple chemical operations. The hNK3 ligands 3 antagonise the calcium mobilisation caused by activation of hNK3 receptors expressed in CHO cells as measured using fura-2 microspectrofluorimetry.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1343-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:9871763-Animals,
pubmed-meshheading:9871763-CHO Cells,
pubmed-meshheading:9871763-Calcium,
pubmed-meshheading:9871763-Cricetinae,
pubmed-meshheading:9871763-Fluorescent Dyes,
pubmed-meshheading:9871763-Fura-2,
pubmed-meshheading:9871763-Humans,
pubmed-meshheading:9871763-Lactams,
pubmed-meshheading:9871763-Molecular Conformation,
pubmed-meshheading:9871763-Receptors, Neurokinin-2,
pubmed-meshheading:9871763-Receptors, Neurokinin-3,
pubmed-meshheading:9871763-Spectrometry, Fluorescence,
pubmed-meshheading:9871763-Structure-Activity Relationship
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pubmed:year |
1998
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pubmed:articleTitle |
High affinity, selective neurokinin 2 and neurokinin 3 receptor antagonists from a common structural template.
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pubmed:affiliation |
Department of Medicinal Chemistry, Merck Sharp Laboratory, Essex, U.K. timothy_harrison@merck.com
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pubmed:publicationType |
Journal Article
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