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rdf:type |
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lifeskim:mentions |
|
|
pubmed:issue |
11
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pubmed:dateCreated |
1999-3-11
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|
pubmed:abstractText |
SAR for antimicrobial activity against H. pylori was investigated in a new series of 2-alkylguanidino-4-furylthiazoles. Of the compounds obtained, cyclohexylmethyl and ethoxyethyl derivatives were identified as a novel class of anti-H. pylori agents which possessed potent and selective antimicrobial activity against H. pylori. These compounds also showed gastric antisecretory activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
|
pubmed:issn |
0960-894X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
2
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1307-12
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9871756-Animals,
pubmed-meshheading:9871756-Anti-Bacterial Agents,
pubmed-meshheading:9871756-Dogs,
pubmed-meshheading:9871756-Gastric Acid,
pubmed-meshheading:9871756-Guanidines,
pubmed-meshheading:9871756-Guinea Pigs,
pubmed-meshheading:9871756-Heart Atria,
pubmed-meshheading:9871756-Helicobacter pylori,
pubmed-meshheading:9871756-Histamine H2 Antagonists,
pubmed-meshheading:9871756-Microbial Sensitivity Tests,
pubmed-meshheading:9871756-Rats,
pubmed-meshheading:9871756-Structure-Activity Relationship,
pubmed-meshheading:9871756-Thiazoles
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|
pubmed:year |
1998
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|
pubmed:articleTitle |
Anti-Helicobacter pylori agents. 2. Structure activity relationships in a new series of 2-alkylguanidino-4-furylthiazoles.
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pubmed:affiliation |
Medicinal Chemistry Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro
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