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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1999-1-26
|
| pubmed:abstractText |
A series of dapsone-related 4-aminopheynl and 2-aminothiazolyl derivatives was prepared, and their antinephritic activity and blood toxicity were evaluated. 5-(2-Pyridylsulfonyl)-2-thiazolamine (FR115092, 26) was effective against two nephritis models, namely graft-versus-host disease (GVHD) and autoimmune W/BF1 mice, and showed none of the blood toxicity observed with dapsone.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
6
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
75-80
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9871632-Anemia,
pubmed-meshheading:9871632-Animals,
pubmed-meshheading:9871632-Disease Models, Animal,
pubmed-meshheading:9871632-Male,
pubmed-meshheading:9871632-Mice,
pubmed-meshheading:9871632-Nephritis,
pubmed-meshheading:9871632-Pyridines,
pubmed-meshheading:9871632-Thiazoles
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Discovery of FR115092: a novel antinephritic agent.
|
| pubmed:affiliation |
Medicinal Chemistry Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan.
|
| pubmed:publicationType |
Journal Article
|