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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1999-1-26
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pubmed:abstractText |
A series of hydroxynaphthazarins has been synthesized. Some of them were found in in vivo experiments to be protectors of myocardium under ischemia-reperfusion and to reduce the infarction zone by 50% without any adverse effect. All compounds exhibit a moderate or small toxicity and are active in low doses.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:AfonskayaN INI,
pubmed-author:Anufriev VPh,
pubmed-author:CherpachenkoN MNM,
pubmed-author:ElyakovG BGB,
pubmed-author:LebedevA VAV,
pubmed-author:LevitskyD ODO,
pubmed-author:MaximovO BOB,
pubmed-author:NovikovV LVL,
pubmed-author:Ruda MYa,
pubmed-author:SadretdinovS MSM,
pubmed-author:ShvilkinA VAV
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pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
587-92
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9871565-Animals,
pubmed-meshheading:9871565-Hydroxylation,
pubmed-meshheading:9871565-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9871565-Male,
pubmed-meshheading:9871565-Mass Spectrometry,
pubmed-meshheading:9871565-Models, Chemical,
pubmed-meshheading:9871565-Myocardial Infarction,
pubmed-meshheading:9871565-Naphthoquinones,
pubmed-meshheading:9871565-Nitroglycerin,
pubmed-meshheading:9871565-Rabbits,
pubmed-meshheading:9871565-Vasodilator Agents,
pubmed-meshheading:9871565-Verapamil
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pubmed:year |
1998
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pubmed:articleTitle |
Synthesis of some hydroxynaphthazarins and their cardioprotective effects under ischemia-reperfusion in vivo.
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pubmed:affiliation |
Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Vladivostok, Russia. anufriev@piboc.marine.su
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pubmed:publicationType |
Journal Article
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