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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1999-1-26
|
| pubmed:abstractText |
A series of 2-phenylbenzofuran derivatives with a diphenylmethylcarbamoyl group at the 5 or 6 position of the benzofuran ring were synthesized and evaluated for rat and human testosterone 5 alpha-reductase inhibitory activities in vitro. They had inhibitory activities against both enzymes and the 6-carbamoyl derivatives tended to be more potent than the 5-carbamoyl compounds.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
17
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
561-6
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:9871560-5-alpha Reductase Inhibitors,
pubmed-meshheading:9871560-Animals,
pubmed-meshheading:9871560-Benzofurans,
pubmed-meshheading:9871560-Carbamates,
pubmed-meshheading:9871560-Enzyme Inhibitors,
pubmed-meshheading:9871560-Humans,
pubmed-meshheading:9871560-Models, Chemical,
pubmed-meshheading:9871560-Models, Molecular,
pubmed-meshheading:9871560-Rats
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Synthesis and 5 alpha-reductase inhibitory activities of benzofuran derivatives with a carbamoyl group.
|
| pubmed:affiliation |
Medicinal Chemistry Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
|
| pubmed:publicationType |
Journal Article
|