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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1999-2-26
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pubmed:abstractText |
Tuberculous meningitis (TBM) remains common in Hong Kong. From January 1996 to June 1997, 11 adult patients with TBM presented to Queen Mary Hospital, a regional hospital in Hong Kong. The annual incidence of TBM was estimated at 1.8 per 100,000 population. Nine patients were local Chinese, and only one patient had the acquired immune-deficiency syndrome (AIDS). In contrast to the classical presentation as a chronic indolent disease, our patients presented acutely: the mean duration from onset of symptoms to presentation was 4.8 days (range 0-10). The most common presenting symptoms were headache (64%), fever (46%), or both (36%), with focal deficits occurring in 64% of patients. Cerebrospinal fluid (CSF) culture and polymerase chain reaction (PCR) were positive in 30% and 29% of cases. Mean CSF cell count, protein and glucose levels were 340 x 10(6)/L, 267 mg/dL, and 2.3 mmol/L, respectively. Extra-neural tuberculosis occurred in 46% of cases. All patients survived and responded to treatment. Drug-induced hepatotoxicity was common; 64% of patients developed biochemical hepatitis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1027-3719
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1040-3
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pubmed:dateRevised |
2006-6-12
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pubmed:meshHeading |
pubmed-meshheading:9869123-Adult,
pubmed-meshheading:9869123-Aged,
pubmed-meshheading:9869123-Antitubercular Agents,
pubmed-meshheading:9869123-Female,
pubmed-meshheading:9869123-Hong Kong,
pubmed-meshheading:9869123-Hospitals, Urban,
pubmed-meshheading:9869123-Humans,
pubmed-meshheading:9869123-Incidence,
pubmed-meshheading:9869123-Male,
pubmed-meshheading:9869123-Middle Aged,
pubmed-meshheading:9869123-Tuberculosis, Meningeal
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pubmed:year |
1998
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pubmed:articleTitle |
Tuberculosis meningitis in Hong Kong: experience in a regional hospital.
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pubmed:affiliation |
Department of Medicine, Queen Mary Hospital, University of Hong Kong, PRC.
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pubmed:publicationType |
Journal Article
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