Linked Life Data

9861267

Source:http://linkedlifedata.com/resource/pubmed/id/9861267

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-1-4
pubmed:abstractText
For many years there was no suitable drug available for the control of onchocerciasis. The advent of Mectizan (ivermectin, MSD; an effective microfilaricide), its registration in October 1987 for the treatment of human onchocerciasis, and its suitability for large-scale application were major break-throughs in the control of human onchocerciasis via chemotherapy. Several studies, both fly-feeding experiments and community trials, have established that Mectizan treatment causes a significant reduction in the transmission of infection. Although long-term treatment in some isolated foci (such as occur in the New World and in some hypo- and meso-endemic areas elsewhere) appears to interrupt transmission, more prolonged treatment is required to prove if transmission can be stopped. Advantage could be taken of the significant impact of Mectizan on transmission by giving treatment while or just before transmission by blackflies is most intense.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-4983
pubmed:author
pubmed:issnType
Print
pubmed:volume
92 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S46-60
pubmed:dateRevised
2009-5-18
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The impact of Mectizan on the transmission of onchocerciasis.
pubmed:affiliation
World Health Organization/Onchocerciasis Control Programme in West Africa, Ouagadougou, Burkina Faso. boatin@ocp.oms.bf
pubmed:publicationType
Journal Article, Review