rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
1998-12-21
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pubmed:abstractText |
To investigate the molecular mechanism relating phenotype and genotype in the rd mouse, mRNA and pre-mRNA levels derived from the wild-type and position-347 nonsense mutant beta-phosphodiesterase (beta-PDE) genes were determined and compared with the corresponding gene copy ratios.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3',5'-Cyclic-GMP Phosphodiesterases,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide...,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Eye Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Pde6b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0146-0404
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2529-36
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9856762-3',5'-Cyclic-GMP Phosphodiesterases,
pubmed-meshheading:9856762-Animals,
pubmed-meshheading:9856762-Cyclic Nucleotide Phosphodiesterases, Type 6,
pubmed-meshheading:9856762-DNA,
pubmed-meshheading:9856762-DNA Primers,
pubmed-meshheading:9856762-Eye Proteins,
pubmed-meshheading:9856762-Female,
pubmed-meshheading:9856762-Gene Dosage,
pubmed-meshheading:9856762-Mice,
pubmed-meshheading:9856762-Mice, Mutant Strains,
pubmed-meshheading:9856762-RNA,
pubmed-meshheading:9856762-RNA, Messenger,
pubmed-meshheading:9856762-Retina,
pubmed-meshheading:9856762-Retinal Degeneration,
pubmed-meshheading:9856762-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
1998
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pubmed:articleTitle |
Selective degradation of nonsense beta-phosphodiesterase mRNA in the heterozygous rd mouse.
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pubmed:affiliation |
Department of Molecular Genetics and Microbiology, University of Florida, Gainesville 32610, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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