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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
6
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pubmed:dateCreated |
1998-12-31
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|
pubmed:abstractText |
Clinical studies suggest that midazolam and propofol interact synergistically to induce hypnosis, but these drugs do not interact synergistically to prevent movement in response to noxious stimuli. The mechanisms underlying these interactions are not certain but may occur at the level of the gamma-aminobutyric acid A (GABA(A)) receptor.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-3022
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
89
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|
pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1444-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9856719-Anesthetics, Intravenous,
pubmed-meshheading:9856719-Animals,
pubmed-meshheading:9856719-Anti-Anxiety Agents,
pubmed-meshheading:9856719-Cells, Cultured,
pubmed-meshheading:9856719-Dose-Response Relationship, Drug,
pubmed-meshheading:9856719-Drug Synergism,
pubmed-meshheading:9856719-Flurazepam,
pubmed-meshheading:9856719-Hippocampus,
pubmed-meshheading:9856719-Membrane Potentials,
pubmed-meshheading:9856719-Mice,
pubmed-meshheading:9856719-Midazolam,
pubmed-meshheading:9856719-Neurons,
pubmed-meshheading:9856719-Patch-Clamp Techniques,
pubmed-meshheading:9856719-Propofol,
pubmed-meshheading:9856719-Receptors, GABA-A
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pubmed:year |
1998
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pubmed:articleTitle |
Isobolographic analysis of the interactions between midazolam and propofol at GABA(A) receptors in embryonic mouse neurons.
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pubmed:affiliation |
Anaesthesia Research Laboratory, University of Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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