pubmed-article:9855366 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0028128 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0085295 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0025056 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0010132 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0439857 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
pubmed-article:9855366 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
pubmed-article:9855366 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:9855366 | pubmed:dateCreated | 1999-3-12 | lld:pubmed |
pubmed-article:9855366 | pubmed:abstractText | Following treatment with interleukin-10 (IL-10), basal corticotrophin releasing factor (CRF) levels from rat hypothalamic median eminence (ME) were found to be increased. Our data show: (1) the specificity of stimulation of CRF through the use of recombinant IL-10 and its blockage by monoclonal anti-IL-10 antibody; (2) the requirement of NO in this process through the use of N(omega)-nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase inhibitor; (3) the blockage of IL-10 stimulated NO production by anti-IL-10; and, (4) the presence of IL-10 transcripts in hypothalamic poly A+ mRNA. These results provide the first evidence of IL-10 acting in the ME to influence CRF levels and further support our earlier findings of a potential for IL-10 in the hypothalamic-pituitary axis. | lld:pubmed |
pubmed-article:9855366 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9855366 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:9855366 | pubmed:language | eng | lld:pubmed |
pubmed-article:9855366 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9855366 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9855366 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:9855366 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9855366 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:9855366 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:9855366 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9855366 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9855366 | pubmed:month | Nov | lld:pubmed |
pubmed-article:9855366 | pubmed:issn | 0304-3940 | lld:pubmed |
pubmed-article:9855366 | pubmed:author | pubmed-author:BeauvillainJ... | lld:pubmed |
pubmed-article:9855366 | pubmed:author | pubmed-author:HughesT KTK | lld:pubmed |
pubmed-article:9855366 | pubmed:author | pubmed-author:StefanoG BGB | lld:pubmed |
pubmed-article:9855366 | pubmed:author | pubmed-author:PrevotVV | lld:pubmed |
pubmed-article:9855366 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9855366 | pubmed:day | 13 | lld:pubmed |
pubmed-article:9855366 | pubmed:volume | 256 | lld:pubmed |
pubmed-article:9855366 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9855366 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9855366 | pubmed:pagination | 167-70 | lld:pubmed |
pubmed-article:9855366 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:9855366 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9855366 | pubmed:articleTitle | Interleukin-10 stimulation of corticotrophin releasing factor median eminence in rats: evidence for dependence upon nitric oxide production. | lld:pubmed |
pubmed-article:9855366 | pubmed:affiliation | Neuroscience Research Institute, SUNY/College at Old Westbury, NY 11568, USA. | lld:pubmed |
pubmed-article:9855366 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9855366 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:9855366 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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