Linked Life Data

9854377

Source:http://linkedlifedata.com/resource/pubmed/id/9854377

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
48
pubmed:dateCreated
1999-1-12
pubmed:abstractText
Further evidence of the transmissibility of bovine spongiform encephalopathy (BSE) across the species barrier from cow to man has been derived from epidemiological analysis and the characterisation of prion strains. Recent research has shown the persistence of prions after experimental transmission to resistant murine species, and subclinical persistence in cows. The accumulation of pathological prion proteins in tonsils and appendix has been demonstrated prior to clinical confirmation of the presence of the new variant of Creutzfeldt-Jakob disease. Current prion research is focused on the involvement of B lymphocytes as carriers, on the species barrier and cellular receptors, and on macromolecules involved in the conformational change from normal to pathological prion proteins.
pubmed:language
swe
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0023-7205
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5499-500, 5503-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[A review of the current research on prions. The evidence suggests the possibility of transmission of the mad cow disease to humans].
pubmed:affiliation
Smittskyddsinstitutet, och mikrobiologiskt och tumörbiologiskt centrum, Karolinska institutet, Solna.
pubmed:publicationType
Journal Article, English Abstract, Review