| pubmed-article:9850996 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0206544 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0086376 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C0728938 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:9850996 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:9850996 | pubmed:issue | 2-4 | lld:pubmed |
| pubmed-article:9850996 | pubmed:dateCreated | 1999-2-4 | lld:pubmed |
| pubmed-article:9850996 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9850996 | pubmed:abstractText | Bovine respiratory syncytial virus (BRSV) strains are tentatively divided in subgroups A, AB and B, based on antigenic differences of the G protein. A Dutch BRSV strain (Waiboerhoeve: WBH), could not be assigned to one of the subgroups, because the strain did not react with any monoclonal antibody against the G protein. We describe here that the WBH strain has accumulated critical mutations in subgroup-specific domains of the G protein gene, which also occur but then independently in G protein genes of BRSV subgroup A or B strains. Although the comparison of nucleotide residues 256-792 of the G gene of the WBH strain with those of subgroup A and B strains showed that the G gene of the WBH strain is different from that of BRSV subgroup A and B strains, the sequence divergence was not more than observed within the G genes of human respiratory syncytial virus subgroup A or B strains. The WBH strain did not induce severe disease after experimental infection of calves, and induced partial protection against a heterologous challenge. Despite the dissimilarity of the conserved central regions of the G protein of the WBH strain and that of the challenge strain, a secondary antibody response against this region was induced in WBH-infected calves after challenge. We conclude that complete BRSV virus can partially protect against a BRSV infection with a strain that contains an antigenic dissimilar G protein. | lld:pubmed |
| pubmed-article:9850996 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9850996 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9850996 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9850996 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9850996 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9850996 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9850996 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9850996 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9850996 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9850996 | pubmed:issn | 0378-1135 | lld:pubmed |
| pubmed-article:9850996 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:9850996 | pubmed:author | pubmed-author:KrampsJ AJA | lld:pubmed |
| pubmed-article:9850996 | pubmed:author | pubmed-author:LangedijkJ... | lld:pubmed |
| pubmed-article:9850996 | pubmed:author | pubmed-author:SchrijverR... | lld:pubmed |
| pubmed-article:9850996 | pubmed:author | pubmed-author:RijsewijkF... | lld:pubmed |
| pubmed-article:9850996 | pubmed:author | pubmed-author:MiddelW GWG | lld:pubmed |
| pubmed-article:9850996 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9850996 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:9850996 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9850996 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9850996 | pubmed:pagination | 159-75 | lld:pubmed |
| pubmed-article:9850996 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:9850996 | pubmed:meshHeading | pubmed-meshheading:9850996-... | lld:pubmed |
| pubmed-article:9850996 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9850996 | pubmed:articleTitle | A bovine respiratory syncytial virus strain with mutations in subgroup-specific antigenic domains of the G protein induces partial heterologous protection in cattle. | lld:pubmed |
| pubmed-article:9850996 | pubmed:affiliation | Department of Mammalian Virology, DLO-Institute for Animal Science and Health (ID-DLO), Lelystad, The Netherlands. r.s.schrijver@id.dlo.nl | lld:pubmed |
| pubmed-article:9850996 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9850996 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:9850996 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9850996 | lld:pubmed |
