rdf:type |
|
lifeskim:mentions |
umls-concept:C0023866,
umls-concept:C0038525,
umls-concept:C0087111,
umls-concept:C0178602,
umls-concept:C0231491,
umls-concept:C0265110,
umls-concept:C0282443,
umls-concept:C0597357,
umls-concept:C0599946,
umls-concept:C0678812,
umls-concept:C1517004,
umls-concept:C1552617,
umls-concept:C2350691,
umls-concept:C2603343
|
pubmed:issue |
6
|
pubmed:dateCreated |
1999-3-12
|
pubmed:abstractText |
Increasing evidence implicates endothelin (ET)-1 in the pathophysiological development of cerebral vasospasm. This study examined the ability of TBC 11251 (TBC), a new ETA receptor antagonist, to prevent vasospasm in a rabbit model of subarachnoid hemorrhage (SAH).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0148-396X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1409-17; discussion 1417-8
|
pubmed:dateRevised |
2008-6-5
|
pubmed:meshHeading |
pubmed-meshheading:9848855-Animals,
pubmed-meshheading:9848855-Basilar Artery,
pubmed-meshheading:9848855-Calcium Signaling,
pubmed-meshheading:9848855-Disease Models, Animal,
pubmed-meshheading:9848855-Dose-Response Relationship, Drug,
pubmed-meshheading:9848855-Drug Evaluation, Preclinical,
pubmed-meshheading:9848855-Endothelin-1,
pubmed-meshheading:9848855-Infusions, Intravenous,
pubmed-meshheading:9848855-Ischemic Attack, Transient,
pubmed-meshheading:9848855-Isoxazoles,
pubmed-meshheading:9848855-Male,
pubmed-meshheading:9848855-Rabbits,
pubmed-meshheading:9848855-Receptor, Endothelin A,
pubmed-meshheading:9848855-Receptors, Endothelin,
pubmed-meshheading:9848855-Subarachnoid Hemorrhage,
pubmed-meshheading:9848855-Thiophenes
|
pubmed:year |
1998
|
pubmed:articleTitle |
Systemic administration of the endothelin-A receptor antagonist TBC 11251 attenuates cerebral vasospasm after experimental subarachnoid hemorrhage: dose study and review of endothelin-based therapies in the literature on cerebral vasospasm.
|
pubmed:affiliation |
Department of Neurosurgery, National Naval Medical Center, Bethesda, Maryland, USA.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Review,
Research Support, Non-U.S. Gov't
|