| pubmed-article:9845536 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0086661 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0007577 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0078056 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0209606 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C2720170 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0392337 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:9845536 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:9845536 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:9845536 | pubmed:dateCreated | 1999-2-5 | lld:pubmed |
| pubmed-article:9845536 | pubmed:abstractText | Very late antigen-4 (VLA-4)/vascular cell adhesion molecule-1 (VCAM-1) are a pair of adhesion molecules mediating cell-cell interaction. The binding activity of each depends on its surface expression, yet integrin activity can also be modulated through inside-out signaling. However, the specific intracellular molecules involved in modulating integrin VLA-4 activation via inside-out signaling or in regulating VCAM-1 expression are poorly understood. We show here that constitutive coexpression of cyclin C and c-Myc in hematopoietic BAF-B03 cells induces homotypic cell adhesion, which results from enhanced VLA-4 ligand-binding activity and induced expression of VCAM-1. Furthermore, regulation of cell adhesion appears to be a feature unique to cyclin C, but not other G1 cyclins, E and D3, and its regulatory function is independent of CDK8 kinase activity. Our results provide a novel role for cyclin C and c-Myc in the regulation of cell adhesion through distinct mechanisms. | lld:pubmed |
| pubmed-article:9845536 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9845536 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9845536 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9845536 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:9845536 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:TanakaYY | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:YamamuraHH | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:TaniguchiTT | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:OkumuraKK | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:LinZ SZS | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:MinamiYY | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:MineSS | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:YagitaHH | lld:pubmed |
| pubmed-article:9845536 | pubmed:author | pubmed-author:MorinobuAA | lld:pubmed |
| pubmed-article:9845536 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9845536 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:9845536 | pubmed:volume | 92 | lld:pubmed |
| pubmed-article:9845536 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9845536 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9845536 | pubmed:pagination | 4700-11 | lld:pubmed |
| pubmed-article:9845536 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:9845536 | pubmed:meshHeading | pubmed-meshheading:9845536-... | lld:pubmed |
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| pubmed-article:9845536 | pubmed:meshHeading | pubmed-meshheading:9845536-... | lld:pubmed |
| pubmed-article:9845536 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9845536 | pubmed:articleTitle | Functional cooperation of cyclin C and c-Myc in mediating homotypic cell adhesion via very late antigen-4 activation and vascular cell adhesion molecule-1 induction. | lld:pubmed |
| pubmed-article:9845536 | pubmed:affiliation | Department of Biochemistry and of Laboratory Medicine, Kobe University, School of Medicine, Kobe, Japan. | lld:pubmed |
| pubmed-article:9845536 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9845536 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
