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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-3
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pubmed:dateCreated |
1999-2-12
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pubmed:abstractText |
The modification of peristaltic activity in the presence of several metal ions has been investigated in the rat intestine by the isolated organ technique. The metals tested modify the intestinal movements: aluminum, chromium, and yttrium cause a decrease of amplitude, while iron showed no effect. By use of microscopic techniques, the presence of yttrium hydroxide was observed in the intestinal tissues. Iron also appears as a precipitate outside of the intestinal serosal, which may explain why iron did not modify the peristaltism. Chromium and aluminum were not apparent to microscope, despite being detected and quantified in the tissues by means of atomic emission spectrometer. We conclude that the trivalent ions of these elements may operate differently on the mechanisms of intestinal contractions: yttrium precipitates in intercellular spaces, iron precipitates outside the intestines, and chromium and aluminum remain in solution and are distributed homogeneously in the smooth intestinal muscle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0163-4984
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-59
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9845462-Aluminum,
pubmed-meshheading:9845462-Animals,
pubmed-meshheading:9845462-Chromium,
pubmed-meshheading:9845462-Electron Probe Microanalysis,
pubmed-meshheading:9845462-Intestine, Small,
pubmed-meshheading:9845462-Iron,
pubmed-meshheading:9845462-Male,
pubmed-meshheading:9845462-Microscopy, Electron,
pubmed-meshheading:9845462-Muscle, Smooth,
pubmed-meshheading:9845462-Peristalsis,
pubmed-meshheading:9845462-Rats,
pubmed-meshheading:9845462-Rats, Wistar,
pubmed-meshheading:9845462-Yttrium
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pubmed:year |
1998
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pubmed:articleTitle |
The effects of aluminum, iron, chromium, and yttrium on rat intestinal smooth muscle in vitro.
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pubmed:affiliation |
Laboratoire de Chimie Générale Appliquée à la Médecine, Faculté de Médecine, Université Henri Poincaré, Vandoeuvre les Nancy, France.
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pubmed:publicationType |
Journal Article,
In Vitro
|