Linked Life Data

9844992

Source:http://linkedlifedata.com/resource/pubmed/id/9844992

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1999-2-11
pubmed:abstractText
Insulin resistance is an important condition which underlies much of the coronary artery disease in affluent societies. We have related insulin resistance, as assessed by fasting plasma insulin, to erythrocyte membrane composition in 54 healthy men and women on a low fat diet. We found a inverse relationship (r = -0.41, P = 0.002) between fasting plasma insulin and the percentage of arachidonic acid in erythrocyte fatty acids. An inverse relationship of similar strength was found with total n-6 fatty acids and a positive relationship was found with the percentage of saturated fatty acids (r = 0.39, P < 0.01). No relationship was found with n-3 fatty acids. We would suggest that n-6 fatty acids, and in particular arachidonic acid, modify the membrane environment of the insulin receptor (or the glucose transporters) so that lower levels of insulin are required for glucose homeostasis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0952-3278
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-4
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Relationship between plasma insulin and erythrocyte fatty acid composition.
pubmed:affiliation
Division of Human Nutrition, Adelaide, South Australia. peter.clifton@dhn.csiro.au
pubmed:publicationType
Journal Article