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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1999-2-12
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pubmed:abstractText |
The lesion is Sjögren's syndrome consists of lymphocytic infiltration and has a pathology characteristic of the potential apoptotic death of salivary gland secretory epithelial cells. To examine the role of the glandular epithelial cells in the pathogenesis of autoimmune exocrinopathy, we studied Fas and Fas ligand (FasL) expression and quantitated the levels of apoptosis in salivary and lacrimal glands from NOD and NOD-scid mice, an animal model that develops a Sjögren's syndrome-like pathology.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
675-81
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9844759-Animals,
pubmed-meshheading:9844759-Antigens, CD95,
pubmed-meshheading:9844759-Apoptosis,
pubmed-meshheading:9844759-Cell Count,
pubmed-meshheading:9844759-DNA Primers,
pubmed-meshheading:9844759-Epithelial Cells,
pubmed-meshheading:9844759-Fas Ligand Protein,
pubmed-meshheading:9844759-Immunoenzyme Techniques,
pubmed-meshheading:9844759-In Situ Nick-End Labeling,
pubmed-meshheading:9844759-Lacrimal Apparatus,
pubmed-meshheading:9844759-Membrane Glycoproteins,
pubmed-meshheading:9844759-Mice,
pubmed-meshheading:9844759-Mice, Inbred BALB C,
pubmed-meshheading:9844759-Mice, Inbred NOD,
pubmed-meshheading:9844759-Mice, SCID,
pubmed-meshheading:9844759-RNA, Messenger,
pubmed-meshheading:9844759-Salivary Glands,
pubmed-meshheading:9844759-Sjogren's Syndrome
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pubmed:articleTitle |
Inappropriate apoptosis of salivary and lacrimal gland epithelium of immunodeficient NOD-scid mice.
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pubmed:affiliation |
Department of Medicine, University of Texas Health Science Center, San Antonio, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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