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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0020792,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0185117,
umls-concept:C0286983,
umls-concept:C0376358,
umls-concept:C0812444,
umls-concept:C1334043,
umls-concept:C1705784,
umls-concept:C1882832,
umls-concept:C2911684
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pubmed:issue |
4
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pubmed:dateCreated |
1998-12-18
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pubmed:abstractText |
We previously isolated the human KAI1 gene encoding a transmembrane protein which suppresses metastatic ability in Dunning R3327 AT6.1 rat prostate cancer cells when transfected into these cells. The AT6.1 subline is one of the more aggressive sublines among the Dunning R-3327 system of rat prostate cancers. This raises the issue of whether downregulation of KAI1 expression consistently occurs during the acquisition of high metastatic ability by members of the Dunning system of rat prostate cancers.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD82,
http://linkedlifedata.com/resource/pubmed/chemical/CD82 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cd82 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
253-60
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:9831222-Amino Acid Sequence,
pubmed-meshheading:9831222-Animals,
pubmed-meshheading:9831222-Antigens, CD,
pubmed-meshheading:9831222-Antigens, CD82,
pubmed-meshheading:9831222-Base Sequence,
pubmed-meshheading:9831222-DNA, Complementary,
pubmed-meshheading:9831222-Forecasting,
pubmed-meshheading:9831222-Humans,
pubmed-meshheading:9831222-Male,
pubmed-meshheading:9831222-Membrane Glycoproteins,
pubmed-meshheading:9831222-Molecular Sequence Data,
pubmed-meshheading:9831222-Prostate,
pubmed-meshheading:9831222-Prostatic Neoplasms,
pubmed-meshheading:9831222-Protein Conformation,
pubmed-meshheading:9831222-Proto-Oncogene Proteins,
pubmed-meshheading:9831222-RNA, Messenger,
pubmed-meshheading:9831222-Rats,
pubmed-meshheading:9831222-Reference Values,
pubmed-meshheading:9831222-Sequence Homology, Amino Acid,
pubmed-meshheading:9831222-Tumor Cells, Cultured
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pubmed:year |
1998
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pubmed:articleTitle |
Identification of the rat homologue of KAI1 and its expression in Dunning rat prostate cancers.
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pubmed:affiliation |
Oncology Center, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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