Linked Life Data

9828134

Source:http://linkedlifedata.com/resource/pubmed/id/9828134

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-1-21
pubmed:abstractText
The murine Ym1 gene belongs to a family of mammalian genes that are homologous to the chitinases from lower organisms, such as insects, nematodes, bacteria, and plants. All of these homologous mammalian proteins (except one member) have no demonstrable chitinase activity and therefore cannot be considered chitinases. The biological functions of these proteins remain unknown. However, these proteins may function through binding to carbohydrate polymers. In an effort to characterize the murine Ym1 gene better, we have delineated its genomic structure. We mapped the chromosomal location of the Ym1 gene to a central region of mouse chromosome 3 (in the region syntenic to human chromosome 1p13) and that of another murine chitinase-like gene, Brp39, to a central region of mouse chromosome 1 (in the region syntenic to human chromosome 1q31). In addition, we identified several genes highly homologous to Ym1 that cluster at the Ym1 locus. We show that these genes are expressed selectively in different mouse tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0888-7543
pubmed:author
pubmed:copyrightInfo
Copyright 1998 Academic Press.
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-22
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes.
pubmed:affiliation
Research and Development, SmithKline Beecham Pharmaceuticals, UE0548, 709 Swedeland Road, King of Prussia, Pennsylvania, 19406, USA. Hua_Ming_Jin-1@sbphrd.com
pubmed:publicationType
Journal Article