| pubmed-article:9827977 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9827977 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:9827977 | lifeskim:mentions | umls-concept:C0005961 | lld:lifeskim |
| pubmed-article:9827977 | lifeskim:mentions | umls-concept:C0199470 | lld:lifeskim |
| pubmed-article:9827977 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:9827977 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:9827977 | pubmed:dateCreated | 1999-2-10 | lld:pubmed |
| pubmed-article:9827977 | pubmed:abstractText | Between 1976 and 1992, 869 patients <19 years of age underwent BMT at the University of Minnesota for a variety of malignant and non-malignant disorders. One hundred and ninety-six required mechanical ventilation (MV) at some time from the start of pre-BMT cyto reduction through the first year following BMT. Reasons for MV included respiratory compromise, upper airway management and non-pulmonary indications for respiratory support. In multivariate models, underlying diagnosis, receipt of HLA-mismatched marrow and the presence of acute graft-versus-host disease (aGVHD) were independent predictors of the need for MV. Indication for MV, underlying diagnosis, and presence of aGVHD were independent predictors of successful extubation. Overall survival at 2 years was 14% among MV patients and 52% among non-MV patients. While the need for MV during BMT reduces the overall likelihood of survival, 40% of children who required MV were successfully extubated; 35% of these extubated patients were long-term survivors. This outcome is better than that reported for adult BMT patients requiring respiratory support, who show survival of <5% at 6 months following BMT. Our data suggest extrapolation of outcome data from adult to pediatric patients is not appropriate and aggressive care of pediatric patients requiring respiratory support is not futile. | lld:pubmed |
| pubmed-article:9827977 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9827977 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9827977 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9827977 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9827977 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9827977 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9827977 | pubmed:issn | 0268-3369 | lld:pubmed |
| pubmed-article:9827977 | pubmed:author | pubmed-author:RamsayN KNK | lld:pubmed |
| pubmed-article:9827977 | pubmed:author | pubmed-author:SYAA | lld:pubmed |
| pubmed-article:9827977 | pubmed:author | pubmed-author:NegliaJ PJP | lld:pubmed |
| pubmed-article:9827977 | pubmed:author | pubmed-author:MertensA CAC | lld:pubmed |
| pubmed-article:9827977 | pubmed:author | pubmed-author:WarwickA BAB | lld:pubmed |
| pubmed-article:9827977 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9827977 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:9827977 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9827977 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9827977 | pubmed:pagination | 787-94 | lld:pubmed |
| pubmed-article:9827977 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:meshHeading | pubmed-meshheading:9827977-... | lld:pubmed |
| pubmed-article:9827977 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9827977 | pubmed:articleTitle | Outcomes following mechanical ventilation in children undergoing bone marrow transplantation. | lld:pubmed |
| pubmed-article:9827977 | pubmed:affiliation | Department of Pediatrics, Medical College of Wisconsin, Milwaukee 53226, USA. | lld:pubmed |
| pubmed-article:9827977 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9827977 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9827977 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
