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rdf:type |
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lifeskim:mentions |
umls-concept:C0001644,
umls-concept:C0035828,
umls-concept:C0039082,
umls-concept:C0040479,
umls-concept:C0178539,
umls-concept:C0332624,
umls-concept:C0376315,
umls-concept:C0522497,
umls-concept:C0682770,
umls-concept:C0872271,
umls-concept:C1280500,
umls-concept:C1527178,
umls-concept:C1623258,
umls-concept:C2348519,
umls-concept:C2697834
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pubmed:issue |
21
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|
pubmed:dateCreated |
1998-12-22
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|
pubmed:abstractText |
This study examines the cellular basis for the phenotypic appearance of broad-based T waves, increased transmural dispersion of repolarization (TDR), and torsade de pointes (TdP) induced by beta-adrenergic agonists under conditions mimicking the LQT1 form of the congenital long-QT syndrome.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
98
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2314-22
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9826320-Adrenergic beta-Agonists,
pubmed-meshheading:9826320-Adrenergic beta-Antagonists,
pubmed-meshheading:9826320-Animals,
pubmed-meshheading:9826320-Disease Models, Animal,
pubmed-meshheading:9826320-Dogs,
pubmed-meshheading:9826320-Dose-Response Relationship, Drug,
pubmed-meshheading:9826320-Electrocardiography,
pubmed-meshheading:9826320-Isoproterenol,
pubmed-meshheading:9826320-KCNQ Potassium Channels,
pubmed-meshheading:9826320-Long QT Syndrome,
pubmed-meshheading:9826320-Membrane Potentials,
pubmed-meshheading:9826320-Mexiletine,
pubmed-meshheading:9826320-Perfusion,
pubmed-meshheading:9826320-Potassium Channel Blockers,
pubmed-meshheading:9826320-Potassium Channels,
pubmed-meshheading:9826320-Potassium Channels, Voltage-Gated,
pubmed-meshheading:9826320-Sodium Channel Blockers,
pubmed-meshheading:9826320-Torsades de Pointes
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pubmed:year |
1998
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pubmed:articleTitle |
Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes.
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pubmed:affiliation |
Masonic Medical Research Laboratory, Utica, NY, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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