|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0019163,
umls-concept:C0023911,
umls-concept:C0026882,
umls-concept:C0062525,
umls-concept:C0209227,
umls-concept:C0209738,
umls-concept:C0332283,
umls-concept:C0332294,
umls-concept:C0332835,
umls-concept:C0376387,
umls-concept:C0521026,
umls-concept:C0683598,
umls-concept:C0870509,
umls-concept:C1517945,
umls-concept:C1705294,
umls-concept:C2745955
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1999-1-7
|
|
pubmed:abstractText |
The purpose of this study was to characterize the clinical, histological and virological events in an orthotopic liver transplant (OLT) recipient with recurrent hepatitis B infection who was initially managed with hepatitis B immune globulin (HBIg) and when viral recurrence occurred, with nucleoside analogue salvage therapy. The aims were to document the mutations occurring in the hepatitis B virus (HBV) polymerase gene as a consequence of HBIg escape, famciclovir non-response and subsequent lamivudine resistance.
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0168-8278
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
669-75
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:9824278-2-Aminopurine,
pubmed-meshheading:9824278-Amino Acid Sequence,
pubmed-meshheading:9824278-Antiviral Agents,
pubmed-meshheading:9824278-DNA, Viral,
pubmed-meshheading:9824278-DNA-Directed DNA Polymerase,
pubmed-meshheading:9824278-Drug Resistance,
pubmed-meshheading:9824278-Hepatitis B,
pubmed-meshheading:9824278-Humans,
pubmed-meshheading:9824278-Immunization, Passive,
pubmed-meshheading:9824278-Immunoglobulins,
pubmed-meshheading:9824278-Lamivudine,
pubmed-meshheading:9824278-Liver,
pubmed-meshheading:9824278-Liver Transplantation,
pubmed-meshheading:9824278-Male,
pubmed-meshheading:9824278-Middle Aged,
pubmed-meshheading:9824278-Molecular Sequence Data,
pubmed-meshheading:9824278-Mutation,
pubmed-meshheading:9824278-Recurrence,
pubmed-meshheading:9824278-Viral Proteins
|
|
pubmed:year |
1998
|
|
pubmed:articleTitle |
The sequential occurrence of viral mutations in a liver transplant recipient re-infected with hepatitis B: hepatitis B immune globulin escape, famciclovir non-response, followed by lamivudine resistance resulting in graft loss.
|
|
pubmed:affiliation |
Department of Hepatogastroenterology, Erasmus University Hospital, Rotterdam, The Netherlands. MAN@INW2.AZR.NL
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|
pubmed:publicationType |
Journal Article,
Case Reports
|
