Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1976-12-30
pubmed:abstractText
A prospective study was performed on 32 consecutive patients undergoing elective operations on the abdominal aorta. Dacron prosthetic grafts were used to replace resected abdominal aortic aneurysms or to bypass aorta-iliac occlusive disease. Complete coagulation studies were performed preoperatively, immediately postoperatively and 24 hours postoperatively. Twenty to 30 per cent of the patients had significant postoperative alterations in prothrombin time, partial thromboplastin time and platelet count. Fibrin monomer, fibrin split products and plasminogen were abnormal in 40 to 80 per cent of the patients postoperatively. Results of preoperative studies showed no significant abnormalities. One of the 32 patients had mild clinical evidence of disseminated intravascular coagulation postoperatively, which was treated with 5 units of heparin per kilogram per hour. Results of the study indicate that aortic grafting procedures frequently produce intravascular coagulation, either local or disseminated. In most patients, this is offset by activation of the fibrinolytic system. However, clinically significant sequelae may result, requiring prompt recognition and treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0039-6087
pubmed:author
pubmed:issnType
Print
pubmed:volume
143
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
730-4
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed-meshheading:982252-Aged, pubmed-meshheading:982252-Aorta, Abdominal, pubmed-meshheading:982252-Aortic Aneurysm, pubmed-meshheading:982252-Aortic Diseases, pubmed-meshheading:982252-Arterial Occlusive Diseases, pubmed-meshheading:982252-Blood Cell Count, pubmed-meshheading:982252-Blood Coagulation Tests, pubmed-meshheading:982252-Blood Platelets, pubmed-meshheading:982252-Blood Vessel Prosthesis, pubmed-meshheading:982252-Disseminated Intravascular Coagulation, pubmed-meshheading:982252-Female, pubmed-meshheading:982252-Fibrin, pubmed-meshheading:982252-Fibrin Fibrinogen Degradation Products, pubmed-meshheading:982252-Fibrinogen, pubmed-meshheading:982252-Humans, pubmed-meshheading:982252-Male, pubmed-meshheading:982252-Middle Aged, pubmed-meshheading:982252-Postoperative Complications, pubmed-meshheading:982252-Prospective Studies, pubmed-meshheading:982252-Prothrombin Time, pubmed-meshheading:982252-Thromboplastin
pubmed:year
1976
pubmed:articleTitle
Intravascular coagulation in surgical procedures on the abdominal aorta.
pubmed:publicationType
Journal Article