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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1999-1-26
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pubmed:abstractText |
We experienced three patients with CD30+ diffuse large cell lymphoma having chromosomal abnormalities. The first patient was an 8-year-old girl with bilateral cervical lymphadenopathy. A biopsy of a cervical lymph node revealed diffuse large cell lymphoma (stage III), positive for CD30 and a chromosomal abnormality, t(2;5). She attained a remission and is now in complete remission 108 months after diagnosis, despite frequent relapses. The second patient was a 13-year-old boy with right axillar and supraclavicular lymph-node adenopathy. A biopsy of a cervical lymph node revealed diffuse large cell lymphoma (stage III), positive for CD30 and a chromosomal abnormality, t(2;5). He attained remission and was in continuous first remission 112 months after diagnosis. The third patient was an 11-year-old boy with fever and bilateral cervical lymph node revealed diffuse large cell lymphoma (stage III), positive for CD30 and chromosomal abnormality without t(2;5). He showed a very aggressive clinical course. Only the patients with Ki-1 lymphoma having t(2;5) survived over 100 months from the diagnosis, despite the advanced stage of the disease. These findings and a review of the literature showed that the presence or absence of t(2;5) may influence the outcome of Ki-1 lymphoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0374-5600
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
474-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9821710-Adolescent,
pubmed-meshheading:9821710-Child,
pubmed-meshheading:9821710-Chromosomes, Human, Pair 2,
pubmed-meshheading:9821710-Chromosomes, Human, Pair 5,
pubmed-meshheading:9821710-Female,
pubmed-meshheading:9821710-Humans,
pubmed-meshheading:9821710-Karyotyping,
pubmed-meshheading:9821710-Lymphoma, Large-Cell, Anaplastic,
pubmed-meshheading:9821710-Male,
pubmed-meshheading:9821710-Prognosis,
pubmed-meshheading:9821710-Survivors,
pubmed-meshheading:9821710-Translocation, Genetic
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pubmed:year |
1998
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pubmed:articleTitle |
Long survivors with Ki-1 lymphoma having t(2;5) (p23;q35). Does the presence or absence of t(2;5) influence the prognosis of patients with Ki-1 lymphoma?
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pubmed:affiliation |
Department of Pediatrics, Kohnan Hospital, Sapporo, Japan. Takaaki.Shikano@ma4.seikyou.ne.jp
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pubmed:publicationType |
Journal Article,
Case Reports
|