|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4265
|
|
pubmed:dateCreated |
1977-1-3
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|
pubmed:abstractText |
When brain synaptosomes are obtained from animals that have been injected intravenously with [2H4]choline 1 minute before being killed, their high affinity [3H] choline uptake is correlated inversely with their acetylcholine content and directly with the rate at which they synthesize [2H4]acetylcholine. The control of such choline uptake by the cytoplasmic acetylcholine concentration is proposed as a mechanism regulating acetylcholine synthesis in cholinergic nerve terminals.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0036-8075
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
5
|
|
pubmed:volume |
194
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
635-7
|
|
pubmed:dateRevised |
2007-3-19
|
|
pubmed:meshHeading |
pubmed-meshheading:982031-Acetylcholine,
pubmed-meshheading:982031-Animals,
pubmed-meshheading:982031-Atropine,
pubmed-meshheading:982031-Biological Transport, Active,
pubmed-meshheading:982031-Brain,
pubmed-meshheading:982031-Choline,
pubmed-meshheading:982031-Electroshock,
pubmed-meshheading:982031-Mice,
pubmed-meshheading:982031-Oxotremorine,
pubmed-meshheading:982031-Pentobarbital,
pubmed-meshheading:982031-Pentylenetetrazole,
pubmed-meshheading:982031-Synaptosomes
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|
pubmed:year |
1976
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|
pubmed:articleTitle |
Regulation of acetylcholine synthesis: does cytoplasmic acetylcholine control high affinity choline uptake?
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|
