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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1999-1-22
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pubmed:abstractText |
Ropivacaine is a new long-acting aminoamide local anaesthetic, structurally related to bupivacaine. The clinical efficacy of 125 mg, 187.5 mg and 250 mg ropivacaine have been reported and compared with 125 mg bupivacaine for epidural analgesia during hysterectomy. In the pharmacokinetic part of this study the objectives were to 1) determine the dose proportionality in the pharmacokinetics of epidural ropivacaine, and 2) compare the pharmacokinetics of 125 mg ropivacaine and 125 mg bupivacaine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0832-610X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
843-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9818106-Adult,
pubmed-meshheading:9818106-Amides,
pubmed-meshheading:9818106-Analgesia, Epidural,
pubmed-meshheading:9818106-Anesthesia, Epidural,
pubmed-meshheading:9818106-Anesthetics, Local,
pubmed-meshheading:9818106-Area Under Curve,
pubmed-meshheading:9818106-Bupivacaine,
pubmed-meshheading:9818106-Chromatography, Gas,
pubmed-meshheading:9818106-Dose-Response Relationship, Drug,
pubmed-meshheading:9818106-Double-Blind Method,
pubmed-meshheading:9818106-Female,
pubmed-meshheading:9818106-Half-Life,
pubmed-meshheading:9818106-Humans,
pubmed-meshheading:9818106-Hysterectomy,
pubmed-meshheading:9818106-Linear Models,
pubmed-meshheading:9818106-Metabolic Clearance Rate,
pubmed-meshheading:9818106-Middle Aged
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pubmed:year |
1998
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pubmed:articleTitle |
Pharmacokinetics of three doses of epidural ropivacaine during hysterectomy and comparison with bupivacaine.
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pubmed:affiliation |
Department of Anaesthesia, Toronto Hospital, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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