Linked Life Data

9817660

Source:http://linkedlifedata.com/resource/pubmed/id/9817660

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-1-11
pubmed:abstractText
We studied the alteration in regional blood flow in minipigs' femur under inadequate decompression after hyperbaric air exposure. The animals were placed in the hyperbaric chamber and exposed to the pressure of 0.5 MPa for 1.5 h, which was reduced to atmosphere at an ascent rate of 0.03-0.04 MPa/min. Regional blood flow in the femur was measured by the isotopes washout method of inhaling 133Xe. The radioactivity was monitored by a multifunctional blood flowmeter interfaced to a minicomputer. Before exposure, the values of average blood flow (F) of femur on the left and right were 15.4 +/- 1.8 and 16.9 +/- 2.0 ml/100 g.min respectively. The values of blood flow (f1) of hematopoietic marrow were 19.1 +/- 2.0 and 21.3 +/- 2.0 ml/100 g.min (n = 7). After inadequate decompression, F values were reduced to 10.3 +/- 1.8 and 11.1 +/- 1.6 ml/100 g.min and f1 values reduced to 13.9 +/- 1.4 and 13.8 +/- 1.0 ml/100 g.min (n = 7), which were obviously lower than those before exposure (P < 0.05). This experiment showed that significant reduction in blood flow in the femur region occurred under inadequate decompression after the exposure of minipigs hyperbaric environment, suggesting that ischemia is a causative factor of osteonecrosis.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1001-5515
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
26-9, 37
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Alteration in regional blood flow in minipigs' femur under inadequate decompression studied by isotopes washout method].
pubmed:affiliation
Institute of Biomedical Engineering, Xi'an Jiaotong University.
pubmed:publicationType
Journal Article, English Abstract