pubmed-article:9815213 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0019351 | lld:lifeskim |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0021051 | lld:lifeskim |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0025266 | lld:lifeskim |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0231220 | lld:lifeskim |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0231221 | lld:lifeskim |
pubmed-article:9815213 | lifeskim:mentions | umls-concept:C0376249 | lld:lifeskim |
pubmed-article:9815213 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:9815213 | pubmed:dateCreated | 1999-1-7 | lld:pubmed |
pubmed-article:9815213 | pubmed:abstractText | Herpes simplex virus (HSV) infection is common in persons coinfected with human immunodeficiency virus (HIV). In a prospective study, daily viral cultures of the mouth, genitals, and rectum were collected from 68 HIV-positive and 13 HIV-negative men who have sex with men. Subjects completed a median of 57 days of follow-up. Anogenital HSV-2 cultures were positive on 405 (9.7%) of 4167 days for HIV-positive men and on 24 (3.1%) of 766 days for HIV-negative men. Most reactivations were perirectal and subclinical. Risk factors for increased HSV-2 shedding among HIV-positive men were low CD4 cell count (odds ratio, 2.5; 95% confidence interval, 1.2-5.4) and antibodies to both HSV-1 and HSV-2 versus HSV-2 only (odds ratio, 1.9; 95% confidence interval, 1.0-3.7). Three isolates obtained from 3 separate subjects were resistant to acyclovir. Thus, subclinical HSV-2 reactivation is an important opportunistic infection in persons with HIV infection. Further studies are necessaryto determine the impact of subclinical HSV-2 reactivation on the natural history of HIV infection. | lld:pubmed |
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pubmed-article:9815213 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9815213 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9815213 | pubmed:language | eng | lld:pubmed |
pubmed-article:9815213 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9815213 | pubmed:citationSubset | AIM | lld:pubmed |
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pubmed-article:9815213 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9815213 | pubmed:month | Dec | lld:pubmed |
pubmed-article:9815213 | pubmed:issn | 0022-1899 | lld:pubmed |
pubmed-article:9815213 | pubmed:author | pubmed-author:CoreyLL | lld:pubmed |
pubmed-article:9815213 | pubmed:author | pubmed-author:HillEE | lld:pubmed |
pubmed-article:9815213 | pubmed:author | pubmed-author:HuH LHL | lld:pubmed |
pubmed-article:9815213 | pubmed:author | pubmed-author:ZehJJ | lld:pubmed |
pubmed-article:9815213 | pubmed:author | pubmed-author:SchackerTT | lld:pubmed |
pubmed-article:9815213 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9815213 | pubmed:volume | 178 | lld:pubmed |
pubmed-article:9815213 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9815213 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9815213 | pubmed:pagination | 1616-22 | lld:pubmed |
pubmed-article:9815213 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:9815213 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9815213 | pubmed:articleTitle | Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivations among human immunodeficiency virus-infected men. | lld:pubmed |
pubmed-article:9815213 | pubmed:affiliation | Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA. schac008@Linti.med.umn.edu | lld:pubmed |
pubmed-article:9815213 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9815213 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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