Linked Life Data

9812975

Source:http://linkedlifedata.com/resource/pubmed/id/9812975

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
47
pubmed:dateCreated
1998-12-21
pubmed:abstractText
Mediator was isolated from yeast on the basis of its requirement for transcriptional activation in a fully defined system. We have now identified three new members of mediator in the low molecular mass range by peptide sequence determination. These are the products of the NUT2, CSE2, and MED11 genes. The product of the NUT1 gene is evidently a component of mediator as well. NUT1 and NUT2 were earlier identified as negative regulators of the HO promoter, whereas mutations in CSE2 affect chromosome segregation. MED11 is a previously uncharacterized gene. The existence of these proteins in the mediator complex was verified by copurification and co-immunoprecipitation with RNA polymerase II holoenzyme.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-9258
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
273
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
30851-4
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae.
pubmed:affiliation
Department of Clinical Chemistry and Transfusion Medicine, Göteborg University, Bruna Stråket 16, 413 45 Göteborg, Sweden. cgustaff@ss.gu.se
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't