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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1998-12-16
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pubmed:abstractText |
Tribulusamides A (1) and B (2), new lignanamides embracing two cinnamic amide parts joined in a cis configuration, were isolated from the fruits of Tribulus terrestris, together with four known compounds, N-trans-feruloyltyramine (3), terrestriamide (4), N-trans-coumaroyltyramine (5), and beta-sitosterol. The structures were elucidated by 2D-NMR spectroscopy. Addition of compounds 1-5, especially 1 and 2, to primary cultured mouse hepatocytes significantly prevented cell death induced by D-galactosamine (D-GalN)/tumor necrosis factor alpha (TNF-alpha).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0032-0943
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
628-31
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:9810268-Animals,
pubmed-meshheading:9810268-Cell Survival,
pubmed-meshheading:9810268-Cells, Cultured,
pubmed-meshheading:9810268-Coumaric Acids,
pubmed-meshheading:9810268-Drugs, Chinese Herbal,
pubmed-meshheading:9810268-Liver,
pubmed-meshheading:9810268-Male,
pubmed-meshheading:9810268-Medicine, Chinese Traditional,
pubmed-meshheading:9810268-Mice,
pubmed-meshheading:9810268-Mice, Inbred ICR,
pubmed-meshheading:9810268-Molecular Structure,
pubmed-meshheading:9810268-Spectrum Analysis
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pubmed:year |
1998
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pubmed:articleTitle |
Tribulusamide A and B, new hepatoprotective lignanamides from the fruits of Tribulus terrestris: indications of cytoprotective activity in murine hepatocyte culture.
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pubmed:affiliation |
Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceutical University, Japan.
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pubmed:publicationType |
Journal Article
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