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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1998-12-23
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pubmed:abstractText |
1. We studied whether a new neurotrophic pyrimidine compound, MS-430, can increase the regeneration length of the transected sciatic nerve in a silicone chamber gap of 14 mm. 2. The average length of regenerated myelinated axons in ten cases was 9.0+/-0 mm in the control group, 2.8+/-1.9 mm in the 1 mg/kg/day of the MS-430 group and 5.0+/-5.1 mm in the 3 mg/kg/day of the MS-430 group, indicating that the average length was significantly larger in the 3-mg group than that in the control group (P<0.05). 3. The results clearly showed that the MS-430 has promoting effects on nerve regeneration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0306-3623
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
821-4
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:9809486-Animals,
pubmed-meshheading:9809486-Axons,
pubmed-meshheading:9809486-Female,
pubmed-meshheading:9809486-Myelin Sheath,
pubmed-meshheading:9809486-Nerve Regeneration,
pubmed-meshheading:9809486-Pyrimidines,
pubmed-meshheading:9809486-Rats,
pubmed-meshheading:9809486-Rats, Wistar,
pubmed-meshheading:9809486-Sciatic Nerve
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pubmed:year |
1998
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pubmed:articleTitle |
Increase of nerve regeneration capacity by new neurotrophic pyrimidine derivative MS-430.
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pubmed:affiliation |
Orthopedic Surgery, Matsuyama Red Cross Hospital, Japan.
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pubmed:publicationType |
Journal Article
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