This preliminary study investigated the ability to elevate the serum homocysteine (H[e]) levels and investigated the increases in postoperative neointimal hyperplasia (IH) in an environment with hyperhomocysteinemia and the resultant restenosis in a rat carotid endarterectomy (CEA) model.
Division of Vascular Surgery, Department of Surgery, and the Department of Pathology, University of Arkansas for Medical Sciences and Veterans Administration Hospital, Little Rock, USA.