pubmed-article:9808478 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0013018 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0037993 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0450127 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0204695 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0522536 | lld:lifeskim |
pubmed-article:9808478 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
pubmed-article:9808478 | pubmed:issue | 8 | lld:pubmed |
pubmed-article:9808478 | pubmed:dateCreated | 1998-11-25 | lld:pubmed |
pubmed-article:9808478 | pubmed:abstractText | We have found that feeding Brown Norway (BN) rat spleen cells to Lewis rats prior to transplanting BN kidneys prolongs allograft survival (mean: 8.8 days in unfed rats, 21 days in the BN cell-fed rats; longest survival: 11 days without allo-feeding vs. 37 days with feeding). We have also found that feeding BN cells both before and after transplantation further extends survival (mean: 38 days; longest survival: 105 days). We also examined the cells infiltrating the grafts during the early stages of the allograft response (day 5). Using flow cytometry, we found a significant decrease in the number of leukocytes infiltrating the transplanted kidneys of fed animals. This decrease was mainly due to a drop in the number of infiltrating T cells. We also found that cytokine mRNA production by the graft-infiltrating lymphocytes, assessed by reverse transcription polymerase chain reaction, showed a significant increase in interleukin-4 and transforming-growth factor-beta mRNA in the graft-infiltrating lymphocytes of fed animals compared with the controls. | lld:pubmed |
pubmed-article:9808478 | pubmed:language | eng | lld:pubmed |
pubmed-article:9808478 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9808478 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9808478 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9808478 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9808478 | pubmed:month | Oct | lld:pubmed |
pubmed-article:9808478 | pubmed:issn | 0041-1337 | lld:pubmed |
pubmed-article:9808478 | pubmed:author | pubmed-author:LeeT DTD | lld:pubmed |
pubmed-article:9808478 | pubmed:author | pubmed-author:CarrR IRI | lld:pubmed |
pubmed-article:9808478 | pubmed:author | pubmed-author:ZhouJJ | lld:pubmed |
pubmed-article:9808478 | pubmed:author | pubmed-author:StadnykA WAW | lld:pubmed |
pubmed-article:9808478 | pubmed:author | pubmed-author:KearseyJ AJA | lld:pubmed |
pubmed-article:9808478 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9808478 | pubmed:day | 27 | lld:pubmed |
pubmed-article:9808478 | pubmed:volume | 66 | lld:pubmed |
pubmed-article:9808478 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9808478 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9808478 | pubmed:pagination | 976-82 | lld:pubmed |
pubmed-article:9808478 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:9808478 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:9808478 | pubmed:articleTitle | Prolongation of survival of primary renal allografts by feeding of donor spleen cells. | lld:pubmed |
pubmed-article:9808478 | pubmed:affiliation | Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada. | lld:pubmed |
pubmed-article:9808478 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9808478 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9808478 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9808478 | lld:pubmed |