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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1998-11-30
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pubmed:abstractText |
Apobec-1 is an RNA-specific cytidine deaminase whose forced overexpression in transgenic animals is associated with hepatic carcinogenesis. Apobec-1 messenger RNA (mRNA) undergoes alternative splicing, generating a catalytically inactive peptide, apobec-T. We have examined apobec-1 gene expression in human gastrointestinal tumors and in colon cancer-derived cell lines.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0016-5085
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1096-103
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9797364-3T3 Cells,
pubmed-meshheading:9797364-Aged,
pubmed-meshheading:9797364-Aged, 80 and over,
pubmed-meshheading:9797364-Alternative Splicing,
pubmed-meshheading:9797364-Animals,
pubmed-meshheading:9797364-Colonic Neoplasms,
pubmed-meshheading:9797364-Cytidine Deaminase,
pubmed-meshheading:9797364-Female,
pubmed-meshheading:9797364-Fetus,
pubmed-meshheading:9797364-Gastrointestinal Neoplasms,
pubmed-meshheading:9797364-Humans,
pubmed-meshheading:9797364-Immunohistochemistry,
pubmed-meshheading:9797364-Male,
pubmed-meshheading:9797364-Mice,
pubmed-meshheading:9797364-Middle Aged,
pubmed-meshheading:9797364-RNA, Messenger,
pubmed-meshheading:9797364-RNA-Binding Proteins,
pubmed-meshheading:9797364-Reference Values,
pubmed-meshheading:9797364-Tumor Cells, Cultured
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pubmed:year |
1998
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pubmed:articleTitle |
An alternatively spliced form of apobec-1 messenger RNA is overexpressed in human colon cancer.
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pubmed:affiliation |
Department of Medicine, University of Chicago, Chicago, Illinois, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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