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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1999-1-4
|
| pubmed:abstractText |
We describe the 5-year mortality and its risk factors in a cohort of elderly people with and without known diabetes mellitus. The PAQUID cohort was representative of the population older than 65 living in Gironde, south-west France. Potential mortality risk factors were collected during a baseline evaluation, using a health questionnaire, from 68.9% of a randomly selected sample of over-65s in 1988. A total of 237 subjects (8.5%) had diabetes. Annual review occurred for 5 years and cause of any death was ascertained from family doctors. After 5 years, 623 people (22.3%) had died, of whom 576 were non-demented; 30.0% of the diabetic group versus 20.3% of the non-diabetic group had died. Survival of the known diabetic group was lower than that of the non-diabetic group (p < 0.001), although this excess mortality was significant only in the 65 to 75 age range (relative risk 1.8; 95% confidence interval 1.2 to 2.8, p = 0.04). Cardiovascular mortality rate did not differ between the diabetic and non-diabetic groups (RR 1.2 [0.8-2.0]). Death related to neoplasia was significantly higher in the known diabetic group (RR 2.2 [1.2-3.3], p = 0.01). In the final model, integrating diabetes as a mortality risk factor in the total cohort, known diabetes at the baseline examination was an independent risk factor for mortality (RR 1.4 [1.0-1.8], p = 0.01), in addition to tobacco use, hypertension and functional dependency. These results confirm suggestions that diabetes increases mortality in the over-65 age group, perhaps with an adverse interaction with other pathology.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0742-3071
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
830-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9796883-Aged,
pubmed-meshheading:9796883-Cause of Death,
pubmed-meshheading:9796883-Cohort Studies,
pubmed-meshheading:9796883-Diabetes Mellitus,
pubmed-meshheading:9796883-Female,
pubmed-meshheading:9796883-France,
pubmed-meshheading:9796883-Geriatric Assessment,
pubmed-meshheading:9796883-Health Status,
pubmed-meshheading:9796883-Health Surveys,
pubmed-meshheading:9796883-Humans,
pubmed-meshheading:9796883-Male,
pubmed-meshheading:9796883-Population Surveillance,
pubmed-meshheading:9796883-Questionnaires,
pubmed-meshheading:9796883-Retrospective Studies,
pubmed-meshheading:9796883-Risk Factors,
pubmed-meshheading:9796883-Sex Factors,
pubmed-meshheading:9796883-Survival Rate,
pubmed-meshheading:9796883-Urban Health
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Five-year mortality in elderly French subjects from the PAQUID epidemiologival survey: the burden of diabetes.
|
| pubmed:affiliation |
Centre de Gériatrie du Centre Hospitalo, Universitaire de Bordeaux, Hôpital Xavier-Arnozan, Pessac, France. jean-paul.emeriau@chu-acquitaine.fr
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|