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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1999-2-10
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pubmed:abstractText |
We have characterized clinical and diagnostic features in 18 cases of Legionella pneumonia. Age average of patients was 62.0 years old (male: female = 14:4) and underlying diseases were observed in 12 patients. Legionella pneumonia were diagnosed in 3, 5, 7 and 9 cases by culture, serum antibody measurement, urinary antigen detection and PCR, respectively. Sixteen cases were caused by L. pneumophila, while the other 2 cases were due to L. bozemanii and L. pneumophila or L. dumoffii. Chest X-rays of those patients showed multiple pneumonia shadows in 14 cases, alveolar shadows in 10 cases, pleural effusion in 5 cases. Blood-gas analysis on admission indicated hypoxemia in all cases with abnormal A-a DO2. Laboratory findings showed abnormal data in WBC, CRP, LDH, CPK and liver function tests (ex. GOT, GPT) in most cases. Serum antibody testing showed positive by 5 weeks after onset of pneumonia, but 10 cases of Legionella pneumonia diagnosed by other techniques were judged to be negative. In urinary antigen detection test, 6 and 2 cases showed positive 1 and 4 weeks after onset of pneumonia, respectively. Macrolide antibiotics were administered in all cases during the episode, but delay of macrolide administration was observed in 3 of 4 cases of dead outcome. Serum antibody measurement, urinary antigen detection and PCR, in addition to culture of bacteria, may be required for exact diagnosis of Legionella infection.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-Quinolones,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Infective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Antibiotics, Antitubercular,
http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Minocycline,
http://linkedlifedata.com/resource/pubmed/chemical/Rifampin
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0047-1852
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2707-17
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pubmed:dateRevised |
2011-7-27
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pubmed:meshHeading |
pubmed-meshheading:9796341-4-Quinolones,
pubmed-meshheading:9796341-Anti-Bacterial Agents,
pubmed-meshheading:9796341-Anti-Infective Agents,
pubmed-meshheading:9796341-Antibiotics, Antitubercular,
pubmed-meshheading:9796341-Erythromycin,
pubmed-meshheading:9796341-Female,
pubmed-meshheading:9796341-Humans,
pubmed-meshheading:9796341-Legionella pneumophila,
pubmed-meshheading:9796341-Legionnaires' Disease,
pubmed-meshheading:9796341-Male,
pubmed-meshheading:9796341-Middle Aged,
pubmed-meshheading:9796341-Minocycline,
pubmed-meshheading:9796341-Rifampin
|
pubmed:year |
1998
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pubmed:articleTitle |
[Legionella pneumonia--epidemiology, clinical characteristics and development of diagnosis].
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pubmed:affiliation |
Department of Microbiology, Toho University School of Medicine.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
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