|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003289,
umls-concept:C0011570,
umls-concept:C0012634,
umls-concept:C0032854,
umls-concept:C0205494,
umls-concept:C0332281,
umls-concept:C0815275,
umls-concept:C0871261,
umls-concept:C1561558,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2607943,
umls-concept:C2911692,
umls-concept:C2926606
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1998-12-30
|
|
pubmed:abstractText |
Late-life depression is associated with increased subcortical white matter hyperintensities. There is some evidence that they are associated with a poorer response to acute treatment. Neurological signs and neuropsychological dysfunction are further evidence of abnormalities in the brain, but they have not been studied in relation to therapy resistance.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0033-2917
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1015-26
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|
pubmed:dateRevised |
2004-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:9794009-Aged,
pubmed-meshheading:9794009-Aged, 80 and over,
pubmed-meshheading:9794009-Antidepressive Agents,
pubmed-meshheading:9794009-Basal Ganglia,
pubmed-meshheading:9794009-Brain,
pubmed-meshheading:9794009-Brain Diseases,
pubmed-meshheading:9794009-Comorbidity,
pubmed-meshheading:9794009-Depressive Disorder,
pubmed-meshheading:9794009-Electroconvulsive Therapy,
pubmed-meshheading:9794009-Female,
pubmed-meshheading:9794009-Humans,
pubmed-meshheading:9794009-Lithium,
pubmed-meshheading:9794009-Male,
pubmed-meshheading:9794009-Neurologic Examination,
pubmed-meshheading:9794009-Neuropsychological Tests,
pubmed-meshheading:9794009-Probability,
pubmed-meshheading:9794009-Prospective Studies,
pubmed-meshheading:9794009-Reticular Formation,
pubmed-meshheading:9794009-Treatment Outcome
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|
pubmed:year |
1998
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|
pubmed:articleTitle |
Is subcortical disease associated with a poor response to antidepressants? Neurological, neuropsychological and neuroradiological findings in late-life depression.
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|
pubmed:affiliation |
University Department of Old Age Psychiatry, Manchester Royal Infirmary.
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pubmed:publicationType |
Journal Article
|
