Linked Life Data

979139

Source:http://linkedlifedata.com/resource/pubmed/id/979139

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1976-12-30
pubmed:abstractText
Mice (C57BL/6N) from a commercial production colony with ulcerative skin lesions were shown to have low level infestations with Myobia musculi. Lesions were abolished by exposure to dichlorvos-impregnated plastic strips. Experimental reinfestation with M musculi resulted in prompt exacerbation of lesions in previously healed mice. Exacerbated lesions were again abolished by subsequent dichlorvos treatments. The histopathology of such lesions was shown to be similar to those in cats allergic to Otodectes cynotis; and a morphologic basis for an allergic interpretation of the myobic lesions in the C57BL/6 mice was described. Other evidence supporting an allergic interpretation included the heritability of susceptibility to such lesions in certain strains, the paucity of mites required for extensive lesions, the chronic duration of infestation required prior to lesion development, and the apparent anamnesis to experimental reinfestation. A large commercial hybrid production colony requiring C57BL/6 females had an incidence of ulcerative lesions (in females) of 20% and depressed reproductive indices. Two 48 hour treatments at an interval of 14 days utilizing dichlorvos-impregnated strips (1 square inch per cage) abolished lesions and elevated production indices for a period of 5 months.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0023-6764
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
725-35
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
The parasitic ecology of the rodent mite, Myobia musculi. III. Lesions in certain host strains.
pubmed:publicationType
Journal Article