Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-12-3
pubmed:databankReference
pubmed:abstractText
Members of the dynamin-related proteins family have been identified in a wide range of organisms, however their precise functions remain elusive. We have identified a new member of that GTPase family in the fission yeast Schizosaccharomyces pombe. We show that Msp1+ is an essential nuclear gene encoding a 101 kDa protein whose closest homologue is the S. cerevisiae MGM1 gene product. We also report that msp1 conditional loss of function affects the maintenance of mitochondrial DNA and leads to growth arrest associated with respiratory deficiency.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-291X
pubmed:author
pubmed:copyrightInfo
Copyright 1998 Academic Press.
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
251
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
720-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9790976-Adenosine Triphosphatases, pubmed-meshheading:9790976-Amino Acid Sequence, pubmed-meshheading:9790976-DNA, Mitochondrial, pubmed-meshheading:9790976-Dynamins, pubmed-meshheading:9790976-Fungal Proteins, pubmed-meshheading:9790976-GTP Phosphohydrolases, pubmed-meshheading:9790976-GTP-Binding Proteins, pubmed-meshheading:9790976-Genes, Essential, pubmed-meshheading:9790976-Genes, Fungal, pubmed-meshheading:9790976-Mitochondria, pubmed-meshheading:9790976-Mitochondrial Proteins, pubmed-meshheading:9790976-Molecular Sequence Data, pubmed-meshheading:9790976-Mutagenesis, pubmed-meshheading:9790976-Saccharomyces cerevisiae Proteins, pubmed-meshheading:9790976-Schizosaccharomyces, pubmed-meshheading:9790976-Schizosaccharomyces pombe Proteins, pubmed-meshheading:9790976-Sequence Homology, Amino Acid
pubmed:year
1998
pubmed:articleTitle
Identification of a fission yeast dynamin-related protein involved in mitochondrial DNA maintenance.
pubmed:affiliation
Institut de Pharmacologie et de Biologie Structurale du CNRS, Université Paul Sabatier, 205, route de Narbonne, Toulouse cedex, 31077, France.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't