Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-12-17
pubmed:abstractText
To investigate whether muscle fiber compositions of various skeletal muscles were correlated with each other and whether muscle fiber type composition was related to the serum thyroid hormone level, fast-twitch fiber dominant rats (FFDR), which had a higher percentage of fast-twitch (FT) fibers in the deep portion of the lateral head of the gastrocnemius muscle (GAS), were compared to a control group. The FFDR group was obtained by the selective breeding for high-percentage FT fibers in the GAS, and the control group was obtained by random breeding from the same base population. The percentages of FT fibers of the GAS, soleus (SOL), vastus intermedius (VI), biceps brachii (BB), rectus abdominis (RA) and extensor digitorum longus (EDL) muscles were analyzed. The percentages of FT fibers of the GAS, SOL, VI and BB in the FFDR group were significantly higher than in the control group (p<0.05), and percent FT fibers of the GAS were significantly correlated with those of the SOL (r = 0.62, p<0.01), VI (r = 0.45, p <0.05) and BB (r = 0.43, p<0.05). On the other hand, no significant differences between FFDR and the control group and no significant correlations with the GAS were observed in percent FT fibers of the RA and EDL. The total 3,3',5-triiodo-L-thyronine (T3) level in FFDR was not significantly different from the control group and was not significantly correlated with the percentage of FT fibers. These data suggest that the percentages of FT fibers of various skeletal muscles are genetically correlated with each other, but some FT muscles are not because they might be close to the upper limits of the genetic adaptive range. In addition, percentages of FT fibers are independent of the total T3 level under physiological conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5180
pubmed:author
pubmed:issnType
Print
pubmed:volume
162
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Hereditary dominance of fast-twitch fibers in skeletal muscles and relation of thyroid hormone under physiological conditions in rats.
pubmed:affiliation
Institute of Health and Sport Sciences, University of Tsukuba, Osaka, Japan. suwa@sports.taiiku.tsukuba.ac.jp
pubmed:publicationType
Journal Article