Linked Life Data

9785504

Source:http://linkedlifedata.com/resource/pubmed/id/9785504

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1998-11-4
pubmed:abstractText
This paper shows that both the infection rate and the rate of virogenesis of African horse sickness virus (AHSV) within vector Culicoides are temperature dependent. As temperature is reduced from permissive levels the lifespan of the vector itself is extended but the rate of virogenesis decreases and infection rate falls dramatically so that at 10 degrees C virtually all midges are free from virus by 13 days post infection (dpi). When vectors that had been kept at this temperature for 35 days were moved to a permissive temperature for 3 days; however, the apparent zero infection rate increased to 15.5%. It therefore appears that at low temperature (< or = 15 degrees C) AHSV does not replicate but virus may persist in some vectors at a level below that detectable by traditional assay systems and when the temperature later rises to permissive levels virus replication is able to commence. On the basis of this information an overwintering mechanism for AHSV is suggested. The temperature at which the immature stages of Culicoides are reared may also influence infection with AHSV. A 5-10 degrees C rise in larval developmental temperature resulted in an increase in oral infection rate of a normally non-vector species of Culicoides, from < 1% to > 10%. A mechanism is suggested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0939-1983
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
155-63
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Effect of temperature on African horse sickness virus infection in Culicoides.
pubmed:affiliation
Institute for Animal Health, Pirbright Laboratory, U.K.
pubmed:publicationType
Journal Article