rdf:type |
|
lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0036770,
umls-concept:C0039597,
umls-concept:C0086418,
umls-concept:C0243092,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0679058,
umls-concept:C1334343,
umls-concept:C1547699,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C2700640
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pubmed:issue |
1
|
pubmed:dateCreated |
1998-12-11
|
pubmed:abstractText |
The cDNA (HED-2) encoding a 20 kDa protein found in mammalian epididymal fluid was isolated from a human testis expression library. It is composed of 1908 bp, containing a reading frame of 1479 bp, coding a polypeptide consisting of 493 amino acids, and assigned the accession number: U15158 by GenBank (Biochem. Mol. Biol. Int. 34, 1131-1136, 1994). HED-2 has 99% identity with the zyxin gene in amino acid sequence, a component of cell junction matrix and a member of the LIM domain protein family. Northern blot analysis of RNAs prepared from various human tissues showed that the HED-2 gene was expressed in all tissues analyzed. Sertoli cells of human testis expressed the gene as determined by an in situ hybridization method. The present study shows that the HED-2 gene is a member of the LIM domain protein family.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Metalloproteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/ZYX protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Zyxin
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
1039-9712
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:9784834-Amino Acid Sequence,
pubmed-meshheading:9784834-Base Sequence,
pubmed-meshheading:9784834-Blotting, Northern,
pubmed-meshheading:9784834-Carrier Proteins,
pubmed-meshheading:9784834-Cytoskeletal Proteins,
pubmed-meshheading:9784834-DNA, Complementary,
pubmed-meshheading:9784834-Glycoproteins,
pubmed-meshheading:9784834-Humans,
pubmed-meshheading:9784834-In Situ Hybridization,
pubmed-meshheading:9784834-Male,
pubmed-meshheading:9784834-Metalloproteins,
pubmed-meshheading:9784834-Molecular Sequence Data,
pubmed-meshheading:9784834-Organ Specificity,
pubmed-meshheading:9784834-RNA, Messenger,
pubmed-meshheading:9784834-Sequence Homology, Amino Acid,
pubmed-meshheading:9784834-Sertoli Cells,
pubmed-meshheading:9784834-Zyxin
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pubmed:year |
1998
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pubmed:articleTitle |
Gene encoding a human testis Sertoli cell component related to LIM domain protein.
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pubmed:affiliation |
National Laboratory of Medical Molecular Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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