rdf:type |
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0017636,
umls-concept:C0028027,
umls-concept:C0030705,
umls-concept:C0031001,
umls-concept:C0040399,
umls-concept:C0054692,
umls-concept:C0145055,
umls-concept:C1627358,
umls-concept:C2349975,
umls-concept:C2603343
|
pubmed:issue |
2
|
pubmed:dateCreated |
1998-12-18
|
pubmed:abstractText |
Nicotinamide (NAM) and carbogen both have been shown to enhance the radiation effect in rodent tumour models and are currently being tested in clinical trials. These agents have demonstrated to act against hypoxia and one of their underlying mechanisms could be an increase of tumour blood perfusion.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0167-8140
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
48
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
135-42
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9783884-Analysis of Variance,
pubmed-meshheading:9783884-Brain Neoplasms,
pubmed-meshheading:9783884-Carbon Dioxide,
pubmed-meshheading:9783884-Cell Hypoxia,
pubmed-meshheading:9783884-Cerebrovascular Circulation,
pubmed-meshheading:9783884-Glioblastoma,
pubmed-meshheading:9783884-Humans,
pubmed-meshheading:9783884-Image Enhancement,
pubmed-meshheading:9783884-Image Processing, Computer-Assisted,
pubmed-meshheading:9783884-Niacinamide,
pubmed-meshheading:9783884-Oxygen,
pubmed-meshheading:9783884-Radiation-Sensitizing Agents,
pubmed-meshheading:9783884-Radiopharmaceuticals,
pubmed-meshheading:9783884-Regional Blood Flow,
pubmed-meshheading:9783884-Technetium Tc 99m Exametazime,
pubmed-meshheading:9783884-Tomography, Emission-Computed, Single-Photon
|
pubmed:year |
1998
|
pubmed:articleTitle |
Lack of perfusion enhancement after administration of nicotinamide and carbogen in patients with glioblastoma: a 99mTc-HMPAO SPECT study.
|
pubmed:affiliation |
Department of Radiotherapy, Academic Medical Center, University of Amsterdam, The Netherlands. M.C.C.Hulshof@amc.uva.nl
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial
|