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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1998-11-25
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pubmed:abstractText |
The authors examined 68 patients aged from 42 to 68 years with ischemic heart disease without a history of myocardial infarction and with angina pectoris of exertion functional class 2-3 and circulatory insufficiency class 2 (according to NYHA criteria). The criteria serving as the reason for relating patients to the follow-up group were left-ventricular end-diastolic volume > 160 ml, ejection fraction < 30%, cardiothoracic index > 0.55, threshold power of endured loads within a range of 71.5 +/- 2.30 watt. After stabilization of the clinical status by means of basic therapy (nitrates, blockers of slow calcium channels, diuretics, antiaggregants), all patients were divided into two follow-up groups. The first group consisted of 36 patients who received renitec (10 mg/24 h), patients of group 2 were given enap in the same dose. The course of treatment lasted 12 weeks. The effectiveness of treatment was controlled by echocardiography according to the standard methods in M- and B-regimens. Analysis of the obtained data showed that within 12-day follow-up renitec demonstrated higher effectiveness and lesser incidence of side-effects than did enap given in the same dose.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0869-2092
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
20-2
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9783102-Adult,
pubmed-meshheading:9783102-Aged,
pubmed-meshheading:9783102-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:9783102-Chronic Disease,
pubmed-meshheading:9783102-Drug Therapy, Combination,
pubmed-meshheading:9783102-Echocardiography,
pubmed-meshheading:9783102-Enalapril,
pubmed-meshheading:9783102-Female,
pubmed-meshheading:9783102-Heart Failure,
pubmed-meshheading:9783102-Hemodynamics,
pubmed-meshheading:9783102-Humans,
pubmed-meshheading:9783102-Male,
pubmed-meshheading:9783102-Middle Aged,
pubmed-meshheading:9783102-Myocardial Ischemia
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pubmed:articleTitle |
[A comparison of the clinical efficacy of enalapril maleate analogs in patients with heart failure and ischemic heart disease].
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pubmed:affiliation |
Department of Pharmacology, Zaporozhe State Medical University, Ukraine.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract
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