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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1998-11-5
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pubmed:abstractText |
We herein report an 18-month-old girl who presented with a retroperitoneal mature teratoma that later developed into an endodermal sinus tumor. Her symptoms included an expanding abdominal girth. The serum levels of alpha-fetoprotein were moderately elevated. The excised specimen was a benign mature cystic retroperitoneal teratoma measuring 18 x 11 x 8 cm in size. A hemorrhagic focus measuring 4 cm in diameter was present, which proved to be the focus of an endodermal sinus tumor histologically. The retroperitoneal mature teratoma observed in this case showed malignant germ-cell differentiation. The above case is thought to be extremely rare, but these findings also suggest the possibility of a mature teratoma presenting as a premalignant condition. The sequence of "mature teratoma--germ-cell malignancy" is thus considered to represent a new potential pattern of early phase of carcinogenesis in teratomas.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0046-8177
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
29
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1167-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9781660-Chorionic Gonadotropin,
pubmed-meshheading:9781660-Cysts,
pubmed-meshheading:9781660-Diagnosis, Differential,
pubmed-meshheading:9781660-Endodermal Sinus Tumor,
pubmed-meshheading:9781660-Female,
pubmed-meshheading:9781660-Humans,
pubmed-meshheading:9781660-Infant,
pubmed-meshheading:9781660-Precancerous Conditions,
pubmed-meshheading:9781660-Retroperitoneal Neoplasms,
pubmed-meshheading:9781660-Teratoma,
pubmed-meshheading:9781660-alpha-Fetoproteins
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pubmed:year |
1998
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pubmed:articleTitle |
An endodermal sinus tumor arising from a mature cystic teratoma in the retroperitoneum in a child: is a mature teratoma a premalignant condition?
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pubmed:affiliation |
Department of Surgery II, Nagasaki University School of Medicine, Sakamoto, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports
|